Quantitative Biology Modules

These modules were developed as part of an HHMI-funded, multi-institutional initiative to integrate quantitative thinking into the introductory biology curriculum. They can be used in whole or in part, in class, in discussion section, or as homework (however, we have some evidence that they are more effective when done in “real time” in class than as homework). Keys to these modules are available for instructors; contact leupen at umbc dot edu. We are eager to hear your experience of using these modules and your suggestions for improvement.

1. Animal Physiology Module. This module focuses on the role of size and surface area in the lives of animals. Animal Physiology- Size and Surface Area FINAL

2. Biodiversity Module. This module explores species-area relationships using log-log graphs and power functions. Biodiversity Module FINAL

3. Cell Structure and Function Module. Here students explore cell signaling pathways in a context that allows the application of both simple linear models and simple statistical analysis. Cell Structure and Function Module Final

4. Diffusion. The goal here is for students to see the absolute dependence of physiology– and life– on diffusion, and see how exponential models can help us understand it. Diffusion Module Final Version

5. Introduction to Mathematical Models: Cell Biology Application. We have two modules that are designed to introduce students to the idea of mathematical modeling; if you use multiple modules, you may want to do one of these two first. This one focuses on a cell biology application, and the other on an ecological application; use whichever one best fits your material. Mathematical Models Cell Application

6. Introduction to Mathematical Models: EcoEvo Application. This has the same mathematical concepts as the above module, but set in an ecology-evolution context instead of a cell biology context, as may be more appropriate for some introductory biology courses. Intro to Mathematical Modelling for EcoEvo

7. Mendelian Genetics. This module gives students practice with calculating and predicting the genotype and phenotype frequencies resulting from monohybrid and dihybrid crosses, as well as calculating and interpreting a chi-square statistical analysis to test hypotheses about independent assortment of traits. Mendelian genetics module

8. Photosynthesis (Plant Physiology). The goal here is to put photosynthesis in a real world context, as well as make conceptual connections between photosynthesis, cellular respiration, and industrial CO2 production. Photosynthesis Module FINAL No answers

9. Population Genetics 1: Breeding Bunnies. Here students explore the effect of natural selection on allele frequencies. Pop Gen1 Breeding Bunnies No answers

10. Population Genetics 2: Drifting Bunnies. This is an optional extension of the above module that adds a layer of complexity (and reality!) in the form of genetic drift. Pop Gen2 Drifting Bunnies FINAL No answers